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KMID : 1188320090030030231
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Gut and Liver
2009 Volume.3 No. 3 p.231 ~ p.234
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A Case of Primary Neuroendocrine Carcinoma of the Gallbladder Associated with Anomalous Union of the Pancreaticobiliary Duct
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Yoon Kyoung-Won
Park Chang-Hwan
Lee Wan-Sik
Joo Young-Eun
Kim Hyeun-Soo
Choi Sung-Kyu
Rew Jong-Sun
Lee Jae-Hyuk
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Abstract
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Primary neuroendocrine carcinoma of the gallbladder is extremely rare because normal gallbladder mucosa does not contain neuroendocrine cells. Neuroendocrine cells can be detected at sites of intestinal metaplasia induced by chronic inflammation, which may be the initial step in the development of neuroendocrine tumor of the gallbladder. Anomalous union of the pancreaticobiliary duct (AUPBD) is an uncommon congenital anomaly that is frequently associated with choledocholithiasis, cholangitis, pancreatitis, and cancer of the gallbladder or bile duct. In AUPBD, cancers of the gallbladder and bile duct can be induced by chronic inflammation. We report herein a case of large-cell neuroendocrine tumor of the gallbladder associated with AUPBD.
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KEYWORD
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Anomalous union, Pancreaticobiliary duct, Neuroendocrine tumor, Gallbladder
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